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L-Isoleucine

Molecular formula diagram of L-Isoleucine

Other Names
Isoleucine, (2S,3S)-2-amino-3-methylpentanoic acid, erythro-L-Isoleucine, 2-Amino-3-methylvaleric acid
Description
L-Isoleucine is one of nine essential amino acids required by the human body to function properly. Due to its unique molecular structure, it is classified as a branched-chain amino acid (BCAA). L-Isoleucine cannot be synthesized by the human body and must be obtained through diet or supplements. It contributes significantly to growth, development, and reproduction.
Molecular Formula
C6H13NO2
Molar Mass
131.175g/mol
Properties
White crystal or crystalline powder
Melting Point
285.5 ºC

Here are some frequently asked questions about L-Malic Acid, including its effects, specific uses, and safety. If you don't find the answer you're looking for, feel free to reach out to us.

A: L-Isoleucine is an essential amino acid crucial for protein synthesis and various metabolic processes.

A: L-Isoleucine supplementation may support muscle growth, energy production, immune function, and metabolic health.

A: Yes, L-Isoleucine is popular in sports nutrition formulations due to its role in muscle repair and energy metabolism.

A: Our L-Isoleucine is meticulously sourced, rigorously tested for purity and potency, and manufactured using state-of-the-art processes to ensure the highest quality standards.

A: Yes, L-Isoleucine is suitable for vegans and vegetarians as it can be derived from plant-based sources or produced through fermentation processes.

A: Some research suggests that L-Isoleucine supplementation may help regulate glucose and lipid metabolism, making it potentially beneficial for individuals with metabolic disorders.

A: L-Isoleucine supplementation is generally well-tolerated, but high doses may cause gastrointestinal discomfort in some individuals.

A: L-Isoleucine can be incorporated into various formulations such as protein powders, nutritional supplements, sports drinks, and functional foods to enhance their nutritional profile and efficacy.

A: A. Absolutely! L-Isoleucine is often utilized in cosmetic formulations for its moisturizing and rejuvenating properties.

A: A. L-Isoleucine is believed to have a positive impact on mental focus and cognition, making it a popular ingredient in certain brain health supplements.

A: A. Yes, our L-Isoleucine Chemical Ingredients are derived from non-GMO sources, ensuring the highest quality and purity.

L-Isoleucine Chemical Ingredients find a wide range of applications across various industries. Here are some of the main applications. We provide high-quality L-Isoleucine chemical ingredients that meet the stringent requirements of different industries, and undergo rigorous testing to ensure purity, safety, and efficacy.
Pharmaceutical Industry
L-Isoleucine may be utilized in pharmaceutical formulations for its potential therapeutic benefits, including wound healing, immune support, and metabolic regulation.
Food and Beverage Industry
L-Isoleucine can be incorporated into functional foods, beverages, and dietary supplements to enhance their nutritional value and promote overall health and wellness.
Animal Health
L-Isoleucine supplementation in animal feed formulations may improve growth performance, feed efficiency, and immune function in livestock and poultry, contributing to enhanced animal health and productivity.
Sports Nutrition
L-Isoleucine is widely used in sports nutrition products such as protein powders, pre-workout supplements, and amino acid blends to support muscle growth, recovery, and performance.

Apart from β-ketothiolase deficiency (McKusick 203750), no genetic anomalies related to L-isoleucine degradation have been documented in humans. A 4-month-old boy, exhibiting mild hypoglycemia, lethargy, and apnea, underwent routine metabolic testing revealing elevated plasma short-chain acylcarnitines (AC) using standard methods. Analysis via tandem mass spectrometry detected heightened levels of five-carbon species in plasma AC, comprising a combination of isovaleryl and/or 2-methylbutyrylcarnitine, with no differentiation possible between the isomers using this technique. Subsequent separation methods confirmed 2-methylbutyrylcarnitine (2-MBC) as the predominant species. Routine urine analysis of the proband consistently showed elevated levels of 2-methylbutyrylglycine (2-MBG) without other diagnostic irregularities. These findings point towards an isolated deficiency in 2-methylbutyryl-CoA dehydrogenase (2-MBCDase). The schematic representation below illustrates the catabolic pathway for L-isoleucine metabolism, with the proband's defect denoted by a cross-hatched box. The numbered reactions encompass: 1. Branched-chain 2-oxyacid dehydrogenase; 2. 2-methylbutyryl-CoA dehydrogenase; 3. β-ketothiolase.

2-Methylbutyryl-Coenzyme A Dehydrogenase Deficiency: A New Inborn Error of L-Isoleucine Metabolism (K Michael Gibson, et al., 2000)