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D-Panthenol
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D-Panthenol

Molecular formula diagram of D-Panthenol

Other Names
Provitamin B5, Dexpanthenol, Bepanthen, Pantothenyl alcohol
Description
D-Panthenol, a synthetic derivative of water-soluble Vitamin B5 (pantothenic acid), serves as both a moisturizer and a promoter of wound healing. Its versatility extends to aiding in skin hydration and repair. This ingredient is compatible with various skin types, including sensitive and reactive skin, effectively combating dryness and dehydration. Its application results in enhanced skin flexibility and resilience.
Molecular Formula
C9H19NO4
Molar Mass
205.251g/mol
Properties
Colorless to slightly yellow transparent viscous liquid
Density
1.2 g mL−1 (at 20 °C)
Boiling Point
118 - 120 °C (271 K)
Melting Point
66 - 69 °C (270 K)

Here are some frequently asked questions about D-panthenol, including its effects, specific uses, and safety. If you don't find the answer you're looking for, feel free to reach out to us.

A: D-Panthenol is a synthetic form of Vitamin B5, prized for its remarkable moisturizing and healing properties in skincare.

A: It deeply hydrates, accelerates wound healing, and enhances the skin's overall health and appearance.

A: Absolutely! D-Panthenol is exceptionally gentle and safe for use on all skin types, including sensitive and reactive skin.

A: Yes, indeed! D-Panthenol can be incorporated into your daily skincare regimen, morning and night, to maintain optimal skin health.

A: Not at all! D-Panthenol is formulated to absorb quickly into the skin, leaving behind a smooth, non-greasy finish.

A: Certainly! D-Panthenol plays well with others and can be seamlessly integrated into your existing skincare routine.

A: While individual results may vary, many users report noticeable improvements in skin hydration and texture within just a few weeks of regular use.

A: Absolutely! D-Panthenol's versatility knows no bounds and is equally effective whether applied to the face, body, or even the hair and nails.

A: Yes, D-Panthenol is generally considered safe for use during pregnancy and breastfeeding. However, we always recommend consulting with your healthcare provider for personalized advice.

A: No, our D-Panthenol products are fragrance-free, ensuring a gentle and irritation-free experience for even the most sensitive noses.

D-Panthenol's versatility extends far beyond its role as a mere skincare ingredient. Its multifaceted benefits make it a staple in various beauty and personal care products. Here's a closer look at the diverse applications of D-Panthenol:
Moisturizer
Provides intense hydration for soft, supple skin.
Wound Healing
From minor cuts and scrapes to more significant wounds, D-Panthenol accelerates the skin's natural healing process. Its regenerative properties aid in tissue repair, reducing the risk of scarring and promoting faster recovery.
Skin Care
Say goodbye to compromised skin barriers with D-Panthenol's reparative prowess. By replenishing essential nutrients and strengthening the skin's natural defenses, it restores balance and vitality to even the most damaged skin.
Anti-Inflammatory
Soothe irritated and inflamed skin with D-Panthenol's calming effect. Whether you're dealing with redness, itching, or sensitivity, products infused with D-Panthenol provide much-needed relief, restoring comfort and balance to your skin.
Hair Care
Elevate your hair care routine with D-Panthenol-infused products. Not only does it strengthen hair strands from within, but it also adds a lustrous shine to your locks, leaving them looking healthy and vibrant.
Sunburn Relief
Products containing D-Panthenol provide instant relief, moisturizing and calming sunburned skin for a faster recovery.
Baby Care
Use baby products containing D-Panthenol to provide gentle yet effective protection and moisturization to ensure your baby's skin remains soft and smooth.
Base Makeup
Use D-Panthenol to lay the perfect foundation for perfect makeup, enhance the durability and wearability of makeup, and ensure a fresh and hydrated complexion all day long.
Aftershave
Products containing D-panthenol soothe and moisturize the skin, minimizing redness and discomfort for a smoother, more comfortable shave.

D-Panthenol, a derivative of vitamin B5 (pantothenic acid), plays an active role in mammalian tissue metabolism through the action of alcohol dehydrogenase and its involvement in coenzyme A biosynthesis. In a study exploring glycerol-induced rhabdomyolysis in rats, severe pathomorphological changes were observed in the kidneys. The accompanying image illustrates a notable increase in kidney size and weight post-rhabdomyolysis, as depicted by the change in relative kidney weight (%) and the appearance of the kidneys on day 8. A significant finding was the dark brown staining of the renal medullary tissue in affected animals, indicative of myoglobin accumulation, contrasting with lighter staining in animals treated with PL. Injection of D-Panthenol into rats with rhabdomyolysis led to a noteworthy reduction in both kidney volume and weight, suggesting a potential therapeutic benefit in mitigating the effects of this condition.

Macromorphological changes in the kidneys 8 days after glycerol-induced rhabdomyolysis and its treatment with D-panthenol (Dmitry S. Semenovich, et al., 2022)