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β-Alanine
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β-Alanine

Molecular formula diagram for beta-alanine

Other Names
Beta-Alanine; 3-Aminopropanoic acid
Description
β-Alanine is a natural amino acid that can exist in a free state in the root nodules of leguminous plants in nature. It also exists in tea, mammalian brain hydrolysates and tobacco leaves. It is mainly produced in the liver in the human body.
Molecular Formula
C3H7NO2
Molar Mass
89.09g/mol
Properties
White crystalline powder
Melting Point
207 °C (405 °F; 480 K) (decomposes)
Solubility in Water
54.5 g/100 mL
Solubility
Soluble in methanol. Insoluble in diethyl ether, acetone

Here are some frequently asked questions about β-Alanine intermediates to give you a deeper understanding of their application, production, and safety:

A: β-Alanine intermediates are vital compounds that are used predominantly in the production of pantothenic acid and coenzyme A, two key substances required for numerous biological functions.

A: β-Alanine intermediates find their primary uses in the pharmaceutical, biochemical, and food industries. Their unique properties make them incredibly versatile.

A: β-Alanine intermediates are produced through a series of chemical reactions intricately designed to ensure the perfect balance of stability and effectiveness.

A: Yes, β-Alanine intermediates are safe for use when used in recommended amounts, adhering to safety guidelines and regulations.

A: β-Alanine intermediates are stable under normal conditions. However, they can react if exposed to certain substances, so it is essential to handle them with care.

A: Yes, β-Alanine intermediates are frequently used as food additives due to their beneficial properties.

A: The shelf life of β-Alanine intermediates can vary based on storage conditions, but it's typically between 1-2 years.

A: To maintain their stability and effectiveness, β-Alanine intermediates should be stored in a cool, dry place away from light.

A: You can order β-Alanine intermediates directly from our company. Our team is here to guide you through the process and answer any questions you may have.

A: Yes, β-Alanine intermediates often find their place in the cosmetics industry as a pH regulator, contributing to the overall quality of various products.

1,3-Propanediol (PDO) intermediates have a broad array of applications, emphasizing their valuable role across many industries. Here are several key uses:
Pharmaceutical Industry
β-Alanine intermediates play a critical role in the production of substances that are vital in the medical field. Their primary use is in the synthesis of pantothenic acid, commonly known as Vitamin B5, and coenzyme A, which are both indispensable in the human body for various biochemical reactions, including energy metabolism and the synthesis of fatty acids. By contributing to the creation of these essential compounds, β-Alanine intermediates indirectly support the treatment of various health conditions and overall wellbeing.
Chemical Industry
β-Alanine intermediates are an integral part of various biochemical processes. They are utilized in laboratories and research centers, contributing to the advancement of science and technology through their involvement in the development of new biochemical compounds and reactions.
Cosmetics
The cosmetics industry also benefits from the unique properties of β-Alanine intermediates. They are commonly used as a pH regulator in various cosmetic products, from skincare items like cleansers and moisturizers to make-up products. By maintaining the optimal pH level, they ensure the efficacy of these products and contribute to the maintenance of healthy skin.
Food and Beverage Industry
Their use extends beyond the pharmaceutical industry, as β-Alanine intermediates are frequently utilized as food additives. Their inclusion in foodstuff contributes to the nutritional value, improving the overall quality of the products. They are often added to fortified foods and dietary supplements to enhance their Vitamin B5 content. This addition not only boosts the nutritional profile of these food products but also ensures a longer shelf life and better taste.
Animal Health
In the field of animal health, β-Alanine intermediates are used in the production of animal feed and supplements, contributing to the overall health and wellbeing of livestock and pets.
Agriculture
β-Alanine intermediates also find their place in the agriculture industry. They are often used in the formulation of certain types of fertilizers and plant growth regulators, contributing to higher crop yield and better quality of produce.

Poly(3-hydroxypropionate) (P3HP), renowned for its strength, flexibility, and impressive tensile properties in film form, can be synthesized via the ring-opening polymerization of β-propiolactone. However, large-scale production using this method faces challenges due to the carcinogenic nature of β-propiolactone. A novel approach involving β-alanine as an intermediate has been proposed, offering benefits such as redox neutrality and independence from vitamin B12. Nonetheless, this alternative pathway encounters hurdles like lower P3HP yield and content compared to traditional methods. Supplementation with β-alanine significantly enhances P3HP production, suggesting potential inefficiencies in pathway activity due to either low enzyme function or insufficient intracellular L-aspartate levels. The accompanying diagram depicts the β-Alanine pathway employed in this investigation. Four L-aspartate decarboxylases (PanD) from E. coli, B. subtilis, P. fluorescens, and C. glutamicum were evaluated. Additionally, the diagram features PP0596, the β-alanine-pyruvate transaminase from Pseudomonas putida; YdfG, the 3-hydroxyacid dehydrogenase from E. coli; PrpE, the propionyl-CoA synthase from E. coli; and PhaC1, the polyhydroxyalkanoate synthase from Cupriavidus necator.

Enhanced poly(3-hydroxypropionate) production via β-alanine pathway in recombinant Escherichia coli (Stephen T. L., et al., 2017)